IgA Nephropathy Recurrence after Transplantation
IgA Nephropathy is a world-wide kidney disease whose relapse rate reaches 40%~50% and even after transplantation, the recurrence rate is, unluckily, 2~41%.
Why IgA Nephropathy recur after transplantation?
IgA nephropathy is a kidney disease that occurs when the IgA deposition damages kidneys. When IgA Nephropathy develops into Renal Failure, kidney transplant will be one choice. However, the trouble is, you may suffer a lot for the donated kidney, that it fails again and your IgA Nephropathy comes back.
Transplanted kidney only replaces the impaired kidneys, but experts find that IgA nephropathy relates to not only kidney, but also immune system.
Actually, the immune system is the cause of impaired kidneys. Immune system works to release antibodies to fight against the virus or bacteria. However, in IgA immune disorder, the immune system releases excessive IgA or failed IgA. And they will lodge in the kidneys and trigger inflammation, causing kidney damages. This is how IgA Nephropathy happens.
Donated kidney even is healthy enough to remove the toxins in your body. However, once the bacteria or virus, such as a cold or any infection, attacks you, it will trigger the excessive IgA production in your blood, which flows to kidneys one more time. And your IgA nephropathy comes back. This is why kidney transplant cannot prevent the IgA Nephropathy relapse.
How to prevent the IgA Nephropathy Recurrence after transplantation?
The key point is to avoid the IgA build-up in your kidneys. The details may include as follows:
Cleanse out the excessive antibodies from your blood. Even though no cold or infection attacks you after transplant, your blood still is filled with the excessive IgA antibodies. You need to use machine to remove them out and avoid them moving to kidneys. Unluckily, dialysis cannot make any difference, but other machines, such as plasma exchange or hemoperfusion does.
Rebuild immune system. Besides the removement of antibodies in the blood, the excessive IgA antibodies producer—abnormal immune system, should be dealt with. And the best solution is to rebuild immune system, thus, you will never worry the cold or infection calling the disease back. If you have interest in “rebuild immune system”, please contact the author. (email:email@example.com or whatsapp+8618703318105)
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